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The altered activity of P53 signaling pathway by STK11 gene mutations and its cancer phenotype in Peutz-Jeghers syndrome

Crossref DOI link: https://doi.org/10.1186/s12881-018-0626-5

Published Online: 2018-08-09

Published Print: 2018-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jiang, Yu-Liang

Zhao, Zi-Ye

Li, Bai-Rong

Yang, Fu

Li, Jing

Jin, Xiao-Wei

Wang, Hao

Yu, En-Da

Sun, Shu-Han

Ning, Shou-Bin http://orcid.org/0000-0001-7204-3956
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81500490)

Application Research of Capital Clinical Character (Z151100004015215)

Annual Project of Airforce General Hospital of PLA (KZ2015026, KZ2016021)

Discipline Construction Project - 1255 of Changhai Hospital (CH125530800)

National Key R&D Program of China (2017YFC1308800)
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Article History

Received: 27 December 2017

Accepted: 13 June 2018

First Online: 9 August 2018

Ethics approval and consent to participate

: This study was approved by the Medical Ethics Committee, Airforce General Hospital of PLA and complied with the Declaration of Helsinki. The approval number of this study is AFGHEC2016145. All of the adult participants and the legal guardians of children participants were informed to participate in this study with written consents.

: Written informed consents for publication of their clinical details and images were obtained from adult participants and the legal guardians of children participants in this study.

: The authors declare that they have no competing interests.

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