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Article History

Received: 14 February 2018

Accepted: 19 July 2018

First Online: 30 July 2018

Ethics approval and consent to participate

: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with Helsinki Declaration of 1975, as revised in 2000. This study was approved by the Institutional Ethics Committee of The Third Xiangya Hospital. Written informed consent was obtained from all subjects enrolled in this study, who agreed to join this study, with the intent of using the medical data for scientific research and publication.

: We confirm that all the patient and 100 control subjects signed written informed consent for publication of their own genetic data, clinical details and/or any accompanying images.

: The authors declare that they have no competing interests.

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