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Article History

Received: 18 September 2019

Accepted: 25 February 2020

First Online: 12 March 2020

Ethics approval and consent to participate

: All the tests performed in the current study involving human participants were reviewed and approved by the Institutional Ethics Committee of Centre for Human Genetics, Bengaluru and in agreement with their ethical standards.According to Indian Council for Medical Research (ICMR) bioethical guidelines (2017), verbal consent (assent) to participate for paediatric patients aged between 7 and 12 years is deemed acceptable. The Institutional Ethics Committee of Centre for Human Genetics, Bengaluru was in agreement with this guideline and written and verbal consent to participate was obtained from the parents or legal guardians for all patients under the age of 16. Written consent to participate was obtained for all patients aged 16 and over.

: A written informed consent for publication of medical data and/or clinical images was obtained from the parents or legal guardians for all paediatric patients under the age of 18. For patients above 18 years of age assent and written consent has been obtained for publication of medical data and /or clinical images.

: The authors declare that they have no competing interests.