Cortez Ferreira, Beatriz https://orcid.org/0009-0006-0740-9310
Matos Silva, Gabriela https://orcid.org/0000-0001-5739-7334
Venda, João
Afonso, Nuno
Leal, Rita
Cerqueira, Sofia
Galvão, Ana
Sá, Helena
Article History
Received: 8 January 2026
Accepted: 27 February 2026
First Online: 6 March 2026
Declarations
:
: This manuscript is a narrative review of the published literature on the role of the complement system in kidney disease, including pathophysiological mechanisms, therapeutic targets, and results of previously published clinical trials. No original research involving human participants or animals was conducted by the authors. Therefore, approval by an Ethics Committee or Institutional Review Board was not required, and informed consent was not applicable.
: Not applicable.
: The authors declare no competing interests.