Li, Juan https://orcid.org/0009-0007-0408-7923
Xu, Qiancheng https://orcid.org/0000-0002-3860-0680
Li, Fangxia
Yang, Tingting
Gao, Chaoqing
Li, Yang
Zhou, Jiajun
Cao, Yuhan
Tong, Changjun
Lu, Weihua https://orcid.org/0000-0002-1776-7051
Wu, Yonggui https://orcid.org/0000-0001-6434-4759
Funding for this research was provided by:
the Anhui Province Clinical Medical Research Translation Special Project (202304295107020001)
the Anhui Province Clinical Medical Research Translation Special Project (202304295107020006)
Key Scientific Research Foundation of the Education Department of Province Anhui (2025AHGXZK30670)
Article History
Received: 1 December 2025
Accepted: 2 March 2026
First Online: 25 April 2026
Declarations
:
: The Institutional Review Boards approved this study of all participating centers: Scientific Research and New Technology Ethics Committee of Wannan Medical College Yijishan Hospital, the lead center (Approval No. 2025-61); Medical Ethics Committee of Wuhu Second People’s Hospital (Approval No. 2025-KY-016); Medical Ethics Committee of Wuhu Jinghu District Hospital (Approval No. 20250124-08); Medical Ethics Committee of Wuhu Guangji Hospital (Approval No. WHGJYY-LLSP-2025-01); and Medical Ethics Committee of Wuhu Traditional Chinese Medicine Hospital (Approval No. YW-2025-002). Written informed consent was obtained from all participants before enrollment. This study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines.
: Not applicable.
: The authors declare no competing interests.