Lin, Yiqi
Li, Binyin
Tang, Huidong
Xu, Qun
Wu, Yuncheng
Cheng, Qi
Li, Chunbo
Xiao, Shifu
Shen, Lu
Tang, Weiguo
Yu, Hui
He, Naying
Lin, Huawei
Yan, Fuhua
Cao, Wenwei
Yang, Shilin
Liu, Ye
Zhao, Wei
Lu, Dong
Jiao, Bin
Xiao, Xuewen
Zhou, Lin
Chen, Shengdi
Funding for this research was provided by:
Clinical Research Center, Shanghai Jiao Tong University School of Medicine (DLY201603)
Article History
Received: 29 April 2017
Accepted: 9 July 2018
First Online: 24 July 2018
Ethics approval and consent to participate
: Conformed to the ethical principles proclaimed in the Declaration of Helsinki in 1964, and revised in Tokyo in 2004, the study protocol has been reviewed and thus approved by independent ethics committees in the Ruijin Hospital, which is the leading center of the study. Before the inclusion, written informed consent forms will be signed by patients or their surrogate family member after a detailed explanation. The SIMPLE study is registered with Chinese TrialExternalRef removedandExternalRef removed(Register number: ChiCTR-INR-16008959 and NCT03119051).
: Not applicable.
: The authors declare that they have no competing interests.
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