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Article History

Received: 4 February 2018

Accepted: 7 January 2019

First Online: 15 January 2019

Ethics approval and consent to participate

: Informed consent was not required by local institutional review boards (IRBs) due to subject anonymity and minimal risk to participants. Use of the registry database and additional medical data including brain images was also approved by the Seoul National University Bundang Hospital IRBs (No. B-1058-312-116).

: Not applicable.

: H.-J.B, the principal investigator, is involved as a member of the steering committee, and/or a site investigator, of multicenter clinical studies sponsored by Otsuka Korea, Bayer Korea, Boehringer Ingelheim Korea, SK Chemicals, ESAI-Korea, Daewoong Pharmaceutical Co. Ltd., Daichi Sankyo, AstraZeneca Korea, Dong-A Pharmaceutical, and Yuhan Corporation. H.-J.B. also served as a consultant or scientific advisory board member, or provided lectures, for Bayer Korea, Boehringer Ingelheim Korea, BMS Korea, Pfizer Korea, AstraZeneca Korea, Covidien Korea, and Daichi Sankyo Korea. PK’s department receives research support from Genentech and Lumosa, and she has received travel support for academic work from Neuravi.

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