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Article History

Received: 9 March 2019

Accepted: 19 July 2019

First Online: 9 August 2019

Ethics approval and consent to participate

: The study was conducted according to the principles expressed in the Declaration of Helsinki and was approved by the local university (Duisburg-Essen) institutional review board.

: Written informed consent was obtained from the patient for publication of this Case Report and any accompanying images and videos. A copy of the written consent is available for review by the Editor of this journal.

: Tim Sinnecker has received travel support from Roche and Actelion, and is employee of the Medical Image Analysis Center in Basel, Switzerland.Jeffrie Hadisurya has received travel funding from Novartis, Teva, Bayer and Biogen.Tilman Schneider-Hohendorf has received research and travel support from Biogen and Novartis.Nicholas Schwab has received travel funding from Novartis, and Biogen.Karsten Wrede reports no disclosures.Oliver Gembruch reports no disclosures.Ralf Gold received speaker’s and board honoraria from Baxter, Bayer Schering, Biogen Idec, CLB Behring, Genzyme, Merck Serono, Novartis, Roche, Stendhal, Talecris, TEVA. His department received grant support from Bayer Schering, BiogenIdec, Genzyme, Merck Serono, Novartis, TEVA. He possesses stock options from Merck Serono and Roche.Kerstin Hellwig reports grants and honoriaria from Biogen, Novartis, Roche, Bayer Healthcare, Teva, Sanofi and Merck.Sara Pilgram-Pastor reports no disclosures.Ortwin Adams reports no disclosures.Philipp Albrecht reports grants, personal fees and non-financial support from Allergan, Biogen, Ipsen, Merz Pharmaceuticals, Novartis, and Roche, personal fees and non-financial support from Bayer Healthcare, and Merck, and non-financial support from Sanofi-Aventis/Genzym.Hans-Peter Hartung has received fees for serving on steering commitees from Biogen Idec, GeNeuro, Sanofi Genzyme, Merck, Novartis Pharmaceuticals, Octapharma, Opexa Therapeutics, Teva Pharmaceuticals, MedImmune, Bayer HealthCare, Forward Pharma, and Roche, fees for serving on advisory boards from Biogen Idec, Sanofi Genzyme, Merck, Novartis Pharmaceuticals, Octapharma, Opexa Therapeutics, Teva Pharmaceuticals, and Roche, and lecture fees from Biogen Idec, Sanofi Genzyme, Merck, Novartis Pharmaceuticals, Octapharma, Opexa Therapeutics, Teva Pharmaceuticals, MedImmune, and Roche.Orhan Aktas has received, with approval by the Heinrich Heine University, advisor fees or honoraria from Almirall, Bayer HealthCare, Biogen, MedImmune, Merck, Novartis, and Teva; research support from Bayer HealthCare, Biogen, Novartis, Roche, and Teva.Markus Kraemer has received, by approval by his hospital, honoria from Bayer Schering, Biogen Idec, Merck Pharma Novartis Pharma, Teva Pharma, Roche Pharma und Shire Deutschland.