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Article History

Received: 2 April 2020

Accepted: 19 August 2020

First Online: 3 September 2020

Ethics approval and consent to participate

: The local ethics committee of Heinrich Heine University Duesseldorf approved this observational case series (Number 4436R). Written informed consent was obtained from all participants in accordance with the Declaration of Helsinki.

: Not applicable.

: All authors declare no competing interests related to the work presented. Financial disclosures unrelated to the work are presented:JL has received honoraria for speaking/consultation from Bayer Healthcare, Boehringer Ingelheim, Allergan, Ipsen, Novartis, Teva and Daiichi-Sankyo as well as travel grants from Bayer Healthcare, Merz, Allergan and Ipsen, outside the submitted work.LG reports no financial disclosures.MW reports no financial disclosures.LB reports no financial disclosures.JG has received travel/meeting/accommodation reimbursements from Biogen, Merck Serono, and Sanofi Genzyme, outside the submitted work.LJ reports no financial disclosures.RG reports no financial disclosures.OA has received honoraria for speaking/consultation and travel grants from Bayer Healthcare, Biogen Idec, Chugai, Novartis, Medimmune, Merck Serono, and Teva and research grants from Bayer Healthcare, Biogen Idec, Novartis, and Teva, outside the submitted work.MG has received honoraria for speaking/consultation from Bayer Healthcare, Boehringer Ingelheim and a research grant from B. Braun, outside the submitted work.SJ has received honoraria for speaking/consultation from Bayer Healthcare, Boehringer Ingelheim, Bristol-Myers Squibb, Alexion, Pfizer, Biogen, and Daiichi-Sankyo as well as travel grants from Bayer Healthcare and Daiichi-Sankyo, outside the submitted work.HPH has outside the work presented here received fees for serving on steering or data monitoring committees from Bayer Healthcare, Biogen, Celgene Receptos, GeNeuro, Sanofi Genzyme, Merck, Novartis, Octapharma, Teva Pharmaceuticals, TG Therapeutics, VielaBio.PA reports grants, personal fees and non-financial support from Allergan, Biogen, Ipsen, Merz Pharmaceuticals, Novartis, and Roche, personal fees and non-financial support from Bayer Healthcare, Merck, and Sanofi-Aventis/Genzyme, outside the submitted work.