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Article History

Received: 19 December 2021

Accepted: 18 May 2022

First Online: 21 June 2022

Declarations

:

: The ethics committee of Ruijin Hospital, affiliated with Shanghai Jiaotong University School of Medicine approved the study (KY2017–143) and all participants gave written informed consent prior to participation. All methods were performed in accordance with the relevant guidelines and regulations.

: Not applicable.

: Kang Ren, Yun Ling, and Zhonglue Chen with GYENNO SCIENCE Co., Ltd. affiliations are current GYENNO SCIENCE employees. All authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interests.