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Article History

Received: 5 December 2025

Accepted: 24 March 2026

First Online: 1 April 2026

Declarations

:

: The manuscript adheres to ethical guidelines as explained in the body of the manuscript: The study was approved by the local ethics committee and institutional review board (IRB) on the basis of central votes from the ethics committee of the Friedrich-Alexander-University Erlangen-Nuremberg (Faculty of Medicine), Germany (Re.No-4409 & 30_16B, 115_17B). Accordingly, informed consent was not needed for this retrospective study. This study was conducted in accordance with the principles of the Declaration of Helsinki.

: Not Applicable.

: Dr. Mrochen reports personal fees from Alexion Pharma Germany GmbH, outside the submitted work; Dr. Volbers reports personal fees from Ipsen Pharma, personal fees from CSL Behring, personal fees from AstraZeneca, non-financial support from AbbVie, personal fees from Boehringer Ingelheim GmbH, personal fees from AbbVie, grants from Bangerter Rhyner Foundation, personal fees from Athersys, Inc., personal fees from Sivantos GmbH, personal fees from Bristol-Myers Squibb GmbH & Co. KGaA, personal fees from University of Bern, outside the submitted work;