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Article History

Received: 16 August 2018

Accepted: 19 December 2018

First Online: 29 December 2018

Authors’ information

: Additional author’s information is not relevant to the interpretation or understanding of this article.

: Ethical approval of the Medical Ethics Committee of the UMC Utrecht has been obtained for this study under registration number 17–592/D, date of approval 28 September 2017. This study is registered in the Dutch trial registry (ExternalRef removed) from 31 August 2018 under registration number NTR6687.Each participating centre will obtain approval of the Medical Ethics Committee of the UMC Utrecht before recruitment of patients can start. Furthermore, each participating centre has to comply to local regulations, most of which involve approval by their Board of Directors to participate in a multicentre trial.Consent to participate is ensured in the following way: eligible women will receive oral and written information from their gynaecologist or fertility physician, and additional counselling will be given by the investigator or research nurse after one week to allow the women to make an informed decision on trial participation. Randomization will then be performed after both the patient and the researcher have signed a written informed consent. Tissue will be stored in the Biobank for future research after patients have given broad written consent.

: Not applicable.

: The authors declare that they have no competing interests.

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