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Detection of chromosomal and gene abnormality with karyotyping, chromosomal microarray analysis and trio-based whole exome sequencing in pregnancies with fetal growth restriction: implications for precise prenatal diagnosis

Crossref DOI link: https://doi.org/10.1186/s12884-025-08164-0

Published Online: 2025-10-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Yangping

Cai, Meiying

Chen, Meihuan

Pan, Xiaohe

Shen, Xuna

Song, Binbin

Cai, Xiaohe

Zhou, Lili

Huang, Hailong
Funding

Funding for this research was provided by:

Wenzhou Department of Science and Technology (Y20220413)
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Text and Data Mining valid from 2025-10-10

Version of Record valid from 2025-10-10
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Article History

Received: 23 February 2025

Accepted: 3 September 2025

First Online: 10 October 2025

Declarations

:

: This study was approved by the Ethics Review Committee of Fujian Maternity and Child Health Hospital (approval number: 2021KRD09001) and Wenzhou Central Hospital (approval number: 2022-090), and all pregnant women received genetic counseling and signed the written informed consent prior to invasive prenatal diagnosis. All procedures performed in this study were conducted following the Declaration of Helsinki and international and national laws, regulations and guidelines for ethical review of studies involving humans.

: Not applicable.

: The authors declare no competing interests.

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