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Article History

Received: 14 February 2025

Accepted: 10 September 2025

First Online: 6 January 2026

Declarations

:

: This study was submitted to and approved by the Ethics Committee of the International Peace Maternal and Child Health Hospital (IPMCH), China Academy of Welfare, with the reference number: (GKLW) 2021-19.This research involved a retrospective analysis utilizing blood samples that had been previously collected for NIPT. Given that the original NIPT samples were obtained with informed consent from pregnant women for the specific purpose of prenatal screening, and considering that this study represents a secondary analysis focused on assessing genetic risk factors for thrombosis in these same pregnant women, no additional consent was required from the women or their guardians for this particular research project.This study was conducted in strict adherence to the principles outlined in the World Medical Association’s Declaration of Helsinki ( ) for medical research involving human subjects and human data.

: Not Applicable. This manuscript only includes de-identified clinical test indicators of participants (without any personal identifiers or details that may compromise anonymity). Therefore, consent for publication from participants is not required.All authors consent to the publication of this manuscript. Written informed consent was obtained from all participants prior to their inclusion in the study. The authors confirm that this work is original, has not been published elsewhere, and is not under consideration by another journal. If accepted, the article will not be published elsewhere in the same form without the copyright holder’s written consent.

: The authors declare no competing interests.