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Article History

Received: 10 April 2017

Accepted: 9 February 2018

First Online: 21 February 2018

Ethics approval and consent to participate

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: The authors of this manuscript have the following competing interests: RM and GN are employees of GlaxoSmithKline (GSK). LB was an employee of GSK at the time of the study. LB and GN hold stock options from GSK. FM is the CEO of Statesia, a consultancy firm who previously worked for GSK, but with regard to this study did not receive any funding from GSK. IDZ is an employee of the public hospitals of Paris and has participated in advisory boards for the pharmaceutical industry including GSK, but with regard to this study did not receive any funding from GSK. LM and PLJ are employees of IQVIA a consultancy firm who previously worked for GSK but with regard to this study, IQVIA did not receive any funding from GSK. GSK developed Pazopanib one of the systemic mRCC treatments. Pazopanib was divested to Novartis in March 2015 before the initiation of this study.

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