van de Sande, A. J. M.
Koeneman, M. M.
Gerestein, C. G.
Kruse, A. J.
van Kemenade, F. J.
van Beekhuizen, H. J.
Article History
Received: 8 January 2017
Accepted: 16 May 2018
First Online: 15 June 2018
Ethics approval and consent to participate
: The medical ethical committee of the Erasmus Medical Centre has approved the study protocol (NL 53792.078.15). The TopIC-2 study is registered at ExternalRef removed (NCT02669459), date of registration 27th January 2017.Prior to registration written informed consent will be obtained in all patients. Currently we are recruiting patients in the Erasmus Medical center and Meander Hospital in Amersfoort, the Netherlands. For both hospital medical ethical approval was obtained.
: The authors declare that they have no competing interests.
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