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Article History

Received: 5 March 2018

Accepted: 10 July 2018

First Online: 18 July 2018

Ethics approval and consent to participate

: The study was approved by the Ethics Committee II at Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany [2016-003F-MA], providing approval for all study sites. The approval was permitted in agreement with the ethics commissions of the State Chamber of Physicians in Baden-Württemberg and the State Chamber of Physicians of the Saarland, as well as with the ethics committe at the Medical Faculty Leipzig, University of Leipzig, Germany. Written informed consent is obtained from all participants.

: Not applicable.

: The GrantPax trial is sponsored by the non-profit AIO-Studien gGmbH and received funding from Celgene Corporation, Summit, NJ, USA, under study contract. Celgene had no role in the study design, and has no role in data collection, management, data analysis and interpretation, or decision to submit results for presentation or publication.NH participated at advisory boards organized by the Celgene Corporation (presentation incl.)JB has received a travel grant from Celgene to the ASCO 2017 meeting.The authors declare that they have no competing interest.

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