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Article History

Received: 15 August 2018

Accepted: 17 October 2018

First Online: 1 November 2018

Ethics approval and consent to participate

: The Center for Research and Advanced Studies (CINVESTAV) fulfill the standards of the Mexican Official Norm (NOM-062-ZOO-1999) “Technical Specifications for the Care and Use of Laboratory Animals” based on the Guide for the Care and Use of Laboratory Animals “The Guide”, 2011, NRC, USA with the Federal Register Number # BOO.02.08.01.01.0095/2014, awarded by the National Health Service, Food Safety and Quality (SENASICA) belong to the Animal Health Office of the Minister of Agriculture, Livestock, Rural Development, Fisheries and Food (SAGARPA), an organization that verifies the state compliance of such NOM in Mexico. The Institutional Animal Care and Use Committee (IACUC) from the CINVESTAV as the regulatory office for the approval of research protocols involving the use of laboratory animals and in fulfillment of the Mexican Official Norm resolved: TO APPROVE THE FOLLOWING RESEARCH PROJECT TITLED: “The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo”. ID Animal use protocol number: 0238–17.

: Not applicable.

: The authors declare that they have no competing interests.

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