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Article History

Received: 28 June 2018

Accepted: 21 December 2018

First Online: 8 January 2019

Ethics approval and consent to participate

: All procedures performed in the current study involving human tumor specimens were in accordance with the ethical standards of the local research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This was performed according to the criteria of the ethics committee of the University Hospital of Cologne.Informed consent was not obtained because this secondary analysis of single protein staining is also regularly performed during pathological diagnostics.

: Not applicable.

: Dr. Zander reports grants from the NRW Government during the conduct of the study; personal fees from Roche, personal fees from Novartis, personal fees from Lilly, personal fees from MSD, personal fees from BMS, personal fees from AstraZeneca, personal fees from Sanofi, outside the submitted work.All other authors declare that they have no conflicts of interest.

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