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Article History

Received: 7 May 2018

Accepted: 19 February 2019

First Online: 12 March 2019

Ethics approval and consent to participate

: Animal care for the mice bearing the BC-PDX tumors, as well as age- and gender-matched control mice, was in accordance with the NIH Guide for the Care and Use of Experimental Animals with approval from the Baylor College of Medicine Institutional Animal Care and Use Committee.

: Not applicable.

: RB, DS, SH, LD, AN, MG, CN, CDA, HT, MR, CKO, MTL, RS, and MVT declare that they have no competing interests. ABR, JLS and EPK are employees of RareCyte, Inc. Non-competing interests: MR reports research funding (to institution) from GlaxoSmithKline and Pfizer and consulting with Genentech, Daiichi, and Macrogenics. CKO reports ownership interests in GeneTex; serving as a chair Data Monitoring Committee for Eli Lilly and as a consultant/advisory board member for Genentech, PUMA, AstraZeneca, Tolmar Pharma, Pfizer, Novartis; and grant funding from Roche, Ventana, and PUMA. MTL has ownership interest (including stock, patents, etc.) in StemMed Holdings, StemMed Ltd., and Tvardi Therapeutics Inc. RS reports research funding from AstraZeneca, GlaxoSmithKline, Gilead Sciences, and PUMA and Consulting/advisory committee member for Macrogenics, and Eli Lilly.

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