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Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo

Crossref DOI link: https://doi.org/10.1186/s12885-019-5811-1

Published Online: 2019-06-27

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Jia-Hong

Huang, Wen-Chien

Bamodu, Oluwaseun Adebayo https://orcid.org/0000-0001-8229-0408
Chang, Peter Mu-Hsin

Chao, Tsu-Yi

Huang, Tse-Hung
Funding

Funding for this research was provided by:

Ministry of Science and Technology, Taiwan (MOST107-2320-B-182A-007)

Chang Gung Memorial Hospital Research Foundation (CMRPG2F0141~2)

Chang Gung Memorial Hospital Research Foundation (CMRPG2D0091~3)

Tri-Service General Hospital (TSGH-C107-030)
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Text and Data Mining valid from 2019-06-27

Version of Record valid from 2019-06-27
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Article History

Received: 13 March 2019

Accepted: 9 June 2019

First Online: 27 June 2019

Ethics approval and consent to participate

: The animal studies were approved by the institutional research ethics committee and performed in strict adherence to the Animal Use Protocol # LAC-2014-0170 according to the U.S. National Institutes of Health <i>Guide for the Care and Use of Laboratory Animals</i>. This study involved no human participant and as such neither informed consent nor ethics approval for same was necessary.

: Not applicable

: The authors declare that they have no competing interests.

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