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Article History

Received: 29 October 2018

Accepted: 6 August 2019

First Online: 30 August 2019

Ethics approval and consent to participate

: <i>Statement on ethics approval for animals.</i>The animal use protocols were approved by the Animal Care Committee, Sickkids Research Institute. Animals were treated per guidelines of Canadian Council on Animal Care (CCAC). This article adheres to the ARRIVE guidelines () for the reporting of animal experiments.<i>Statement on ethics approval and consent for human tissues.</i>This study was approved by approved by the Washington University School of Medicine Internal Review Board (IRB No: 201108108) on 09-JUL-2013, prior to any sample collection. The tumor sample patient used in the study were collected by Dr. Ramaswamy Govindan, Division of Oncology, Washington University, Medical School, Washington, USA for the purpose of research. This study did not involve the diagnosis and treatment of patients. Informed consent was waived by the ethics committee of The Hospital for Sick Children, Toronto, Canada.

: No applicable.

: The authors declare that they have no competing interests.