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Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative period

Crossref DOI link: https://doi.org/10.1186/s12885-019-6045-y

Published Online: 2019-08-20

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Niavarani, Seyedeh Raheleh

Lawson, Christine

Bakos, Orneala

Boudaud, Marie

Batenchuk, Cory

Rouleau, Samuel

Tai, Lee-Hwa https://orcid.org/0000-0002-1176-4941
Funding

Funding for this research was provided by:

Canadian Institutes of Health Research (Project Scheme Grant, New Investigator Award)

Fonds de Recherche du Québec - Santé (Researcher/Scholar Junior 1)

Cancer Research Society (Operating Grant)

Universite de Sherbrooke (Faculty of Medicine and Health Sciences)

Natural Sciences and Engineering Research Council of Canada (Discovery Grant)
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Article History

Received: 15 April 2019

Accepted: 16 August 2019

First Online: 20 August 2019

Ethics approval

: Mice were housed in pathogen-free conditions at the Central Animal Care Facility of the Université de Sherbrooke (Quebec) and the Animal Care Veterinary Service facility of the University of Ottawa (Ontario). All studies and manipulations performed on animals were conducted in accordance with university guidelines and approved by the Animal Care Committee at both universities. Human whole blood was collected (CIPO study, #2017–1506 approved by the ethics board of CIUSSS de l’Estrie CHUS. Informed and written consent to participate in this study was obtained from all participants.

: Informed consent for publication was obtained from all participants in the study.

: The authors declare that they have no competing interests.

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