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Authors
Das, Krishna
Eisel, David
Vormehr, Mathias
Müller-Decker, Karin
Hommertgen, Adriane
Jäger, Dirk
Zörnig, Inka
Feuerer, Markus
Kopp-Schneider, Annette
Osen, Wolfram
Eichmüller, Stefan B. https://orcid.org/0000-0002-3497-6904
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Funding
Funding for this research was provided by:
Helmholtz International Graduate School for Cancer Research
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Article History
Received: 9 April 2019
Accepted: 28 August 2019
First Online: 13 September 2019
Ethics approval and consent to participate
: The physiological interactions between T cells and tumor-associated macrophages can only be investigated within the mammalian animal model, as it provides a complete immune system including the entirety of its complex interactions. Still, performance of the animal experiments followed the 3R principle, in order to minimize the number of animals recruited for the experiments and to reduce their burden.The mice were housed and treated at the DKFZ animal facility. Animal experiments were approved by the District Government (Regierungspräsidium Karlsruhe) in Karlsruhe, Germany (approval ID 35–9158.81/G172–12).
: Not applicable.
: The authors declare that they have no competing interests.
