Document is current

Article History

Received: 6 December 2019

Accepted: 9 March 2020

First Online: 18 March 2020

Ethics approval and consent to participate

: As noted in the manuscript, all analyses involving human patient samples and clinical data were performed in accordance with the ethical standards and the local Institutional Review Board (IRB)-approved protocols of the Medical Faculty of RWTH Aachen University (RWTH EK 009/12) and of the Heinrich Heine University Düsseldorf (IRB approval: April 16 2014). The index patient provided written informed consent for the use of both patient material as well as medical data acquired by examination at the university hospital Düsseldorf starting in 2009 and gave verbal consent for publication in accordance with the local ethics committee of the Heinrich Heine University Düsseldorf. Finally the patient passed away before a written consent for publication could be realized.

: Not applicable.

: ME: Financial interest and/or other relationship with Astra Zeneca, Janssen, Roche Pharma, MSD, Genomic Health, GN: Financial interest and/or other relationship with BMS, Roche Pharma, MSD; NTG: Financial interest and/or other relationship with Astra Zeneca. All other authors declare no conflict of interest.