Document is current

Article History

Received: 1 May 2020

Accepted: 20 October 2020

First Online: 11 November 2020

Change Date: 29 December 2020

Change Type: Update

Change Details: Open Access funding statement has been added.

Ethics approval and consent to participate

: The study was approved by the relevant ethics committees (ethics committee university clinic Tuebingen: 234/2014BO1). All of the patients provided written informed consent. The consent procedure included the information that the disease, tumor characteristics and biomaterial are used for both scientific projects and eligibility assessments for clinical trials and other treatment opportunities.

: Not applicable.

: E.B. has received honoraria from Novartis, Celgene, Riemser, Pfizer, Hexal, Amgen, onkowissen.de for consulting, clinical research management or medical education activities. M.W.B.’s institution has received research funding from Novartis and BioNTech. J.E. has received honoraria from Roche, Celgene, Novartis, Pfizer, Pierre Fabre, Teva, and travel support from Celgene, Pfizer, Teva, and Pierre Fabre. T.N.F. has received honoraria from AstraZeneca, Celgene, Eisai, Pfizer, and Roche. P.A.F. reports grants from Novartis, Cepheid, and BioNTech, personal fees from Novartis, Roche, Pfizer, Celgene, Daiichi-Sankyo, Teva, AstraZeneca, Merck Sharp & Dohme, Pierre-Fabre, Macrogenics, Eisai, and Puma. A.D.H. has received honoraria from Teva, Genomic Health, Celgene, AstraZeneca, Novartis, Pfizer, Lilly, MSD, Eisai and Roche. J.H. has received honoraria from Novartis, Roche, Celgene, Teva, and Pfizer and travel support from Roche, Celgene, and Pfizer. W.J. has received honoraria and research grants from Novartis. C.M.K. has received honoraria from Amgen, Eli Lilly, Novartis, Mundipharma, Pfizer, PharmaMar, Riemser, Roche and Tesaro and had consulting or advisory role for Amgen, Axios, Eli Lilly, Hilotherm, Mundipharma, NewCo, Novartis, Pfizer, Riemser, Roche and Tesaro. He received research funding from Astra Zeneca, Axios, MSD Sharp & Dohme, NewCo, Novartis, Pfizer, PharmaMar, Riemser, Seattle Genetics and travel or accommodation expenses from Amgen, Hexal, Pfizer, PharmaMar, Tesaro, TEVA Oncology. H.-C.K. has received honoraria from Carl Zeiss meditec, Teva, Theraclion, Novartis, Amgen, AstraZeneca, Pfizer, Janssen-Cilag, GSK, LIV Pharma, Roche, MSD, SurgVision, Onkowissen and Genomic Health. D.L. has received honoraria from Amgen, AstraZeneca, Celgene, Lilly, Loreal, MSD, Novartis, Pfizer, Tesaro, and Teva. M.P.L. has received honoraria from Lilly, Pfizer, Roche, MSD, Hexal, Novartis, AstraZeneca, Eisai, medac, and Genomic Health for advisory boards, lectures and travel support. V.M. has received speaker honoraria from Amgen, AstraZeneca, Celgene, Daiichi-Sankyo, Eisai, Pfizer, Pierre Fabre, Novartis, Roche, Teva, and Janssen-Cilag and consultancy honoraria from Genomic Health, Roche, Pierre Fabre, Amgen, Daiichi-Sankyo, and Eisai. F.O. has received speaker and consultancy honoraria from Amgen, Celgene, AstraZeneca, Novartis, Roche, and MSD. A.S. has received honoraria from Roche, Celgene, AstraZeneca, Novartis, Pfizer, Zuckschwerdt Verlag GmbH, Georg Thieme Verlag, Aurikamed GmbH, MCI Deutschland GmbH, bsh medical communications GmbH, and promedicis GmbH. H.T. has received honoraria from Novartis, Roche, Celgene, Teva, and Pfizer and travel support from Roche, Celgene, and Pfizer. M.W. has received speaker honoraria from AstraZeneca, Celgene, and Novartis. G.K. was an employee at Merrimack Pharmaceuticals. All of the remaining authors (H.H., B.V., F.A.T., L.H., M.R., M.U., D.W., S.Y.B. have declared that they have no conflicts of interest.