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Article History

Received: 1 March 2022

Accepted: 18 October 2022

First Online: 14 December 2022

Declarations

:

: All patients provided written informed consent before enrollment in the clinical trials. The study protocols and all amendments were approved by the institutional review board or ethics committee at each institution. The studies were conducted in accordance with the protocols, their amendments, the ethical principles originating from the Declaration of Helsinki and Good Clinical Practice guidelines.

: <b>RC</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, and has stock ownership interests in Merck & Co., Inc., Rahway, NJ, USA.<b>XQL</b> is an employee of MSD R&D (China) Co. Ltd., a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.<b>GA</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, and has stock ownership interests in Merck & Co., Inc., Rahway, NJ, USA.<b>CC</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.<b>AA</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA.<b>PQ</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, and has stock ownership interests in Merck & Co., Inc., Rahway, NJ, USA.<b>MJM</b> is an employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, has stock ownership interests in Merck & Co., Inc., Rahway, NJ, USA as well as Fulgent Genetics Inc and Q2 Holdings Inc.