Document is current

Article History

Received: 13 June 2022

Accepted: 24 October 2022

First Online: 14 November 2022

Declarations

:

: The trial will be performed in accordance with the recommendations guiding physicians in biomedical research involving human subjects, adopted by the 18^th World Medical Association General Assembly, Helsinki, Finland and stated in the respective participating countries laws governing human research, and Good Clinical Practice. The protocol has been approved by the UK (London Bridge Research Ethics Committee on 28-Sep-2020), New Zealand (Northern B Health and Disability Ethics Committee on 07-Oct-2021) and Denmark (National Center for Ethics on 25-Jul-2022). Competent Authority approval was initially granted in the UK by the Medicines and Healthcare Products Regulatory Agency (MHRA) on 06-Oct-2020; the current protocol (v4.0) was approved on 25-Mar-2021, New Zealand Auckland District Health Board (ADHB) approval was granted on 11-Oct-2021, with Danish approval granted by the Danish Medicines Agency on 22-Jun-2022.All patients provide written informed consent to participate.

: Not applicable.

: CC has received research funding from AbbVie. RD received an educational to support this trial by AbbVie, who provide venetoclax free-of-charge for use within the trial. All other authors declare no competing interests.