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Article History

Received: 7 July 2023

Accepted: 18 December 2023

First Online: 2 January 2024

Declarations

:

: Prior to their participation, patients provided informed consent, and the collection of tumor samples and all experimental procedures strictly adhered to ethical guidelines and local regulations. The study received official approval from the following local research ethics committees: the National Committee for Ethics in Research (CNER) Luxembourg, under the protocol number 201201/06, and the Haukeland University Hospital, under the protocol number 2009/117. Animal experiments were performed in accordance with the 3R rules and the regulations of the European Directive on animal experimentation (2010/63/EU). Animal protocols were rigorously approved by the local ethics committees in compliance with national regulations at two stages: (i) the ‘Animal Welfare Structure’ of the Luxembourg Institute of Health and (ii) by the joint evaluation of the Luxembourg Ministry of Agriculture and the Luxembourg Ministry of Health (protocols: LRNO-2014-01, and LRNO-2016-04). The ARRIVE guidelines were applied for reporting of the findings.

: Not applicable.

: AG acts as a guest editor in the <i>BMC Cancer</i> collection: “<i>Advances in preclinical cancer models</i>”. AO, PMS, VB and SPN have no competing interest.