Document is current
Any future updates will be listed below
-
Authors
Deng, Changmi
Zhu, Jinhong
Duan, Fei
Zhang, Wenli
Zhou, Haixia
Li, Suhong
Zhang, Jiao
Cheng, Jiwen
Fu, Wen
He, Jing
Niu, Huizhong
Hua, Rui-Xi https://orcid.org/0000-0001-5319-656X
-
Funding
Funding for this research was provided by:
Guangzhou Municipal Science and Technology Project (SL2024A04J02146)
Major Science and Technology Special Project of Wenzhou (ZY2020021)
Youth Medical Innovation and Practice Research Program of Guangzhou (2023QNYXYB010)
National Natural Science Foundation of China (82003523)
- License Information
-
More Information
Article History
Received: 3 December 2024
Accepted: 12 March 2025
First Online: 17 March 2025
Declarations
:
: The study followed the Declaration of Helsinki guidelines and was approved by the Ethics Committee of Guangzhou Women and Children Medical Center (No. 202016601). Informed consent was signed by the parents or legal guardians of all the participants.
: Not applicable.
: The authors declare no competing interests.
: This is the first Wilms tumor-specific study on NAT10 gene rs8187 G > A polymorphism. In this five-center case-control study with 414 Wilms tumor cases and 1199 controls, we found that NAT10 gene rs8187 G > A polymorphism is significantly correlated with a decreased risk of developing Wilms tumor, which is more prominent in children aged 18 months or under and in subgroups with stage II, stage IV, or combined stage I + II tumors.
