Dawood, Shakira https://orcid.org/0009-0008-4519-9398
McMillan, Brigid https://orcid.org/0009-0001-0623-6343
Brown, Karryn https://orcid.org/0000-0002-6132-4717
Oosthuizen, Jenna https://orcid.org/0000-0001-7181-3015
Richardson, David https://orcid.org/0009-0005-6453-9173
Simba, Kudakwashe https://orcid.org/0000-0003-1829-154X
Andera, Lillian F. https://orcid.org/0000-0002-8608-6233
Opie, Jessica https://orcid.org/0000-0002-1408-2604
Antel, Katherine https://orcid.org/0000-0002-9000-5504
More, Stuart https://orcid.org/0000-0001-6957-916X
Allie, Ayesha https://orcid.org/0000-0002-3376-0992
Mohamed, Zainab https://orcid.org/0000-0003-4730-4231
Verburgh, Estelle https://orcid.org/0000-0003-4657-7318
Funding for this research was provided by:
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Fogarty International Centre and National Heart, Lung & Blood Institute of the National Institutes of Health (D43 TW010345)
Bristol Myers Squibb Foundation
the BLOODSA Foundation
Cancer Association of South Africa
South African Medical Research Council
Article History
Received: 12 June 2025
Accepted: 19 October 2025
First Online: 25 November 2025
Change Date: 11 December 2025
Change Type: Update
Change Details: The original article has been updated.
Change Date: 21 January 2026
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1186/s12885-025-15452-7
Declarations
:
: This study was approved by the Human Research Ethics Committee of the University of Cape Town (HREC 659/2022) and GSH. A retrospective waiver of informed consent was granted for patients included in the HPR before 2018. Written informed consent was obtained for patients included from 2018 onwards. The study adhered to the Declaration of Helsinki.
: Not applicable.
: The authors declare no competing interests.