Zhang, Yusong
He, Jiajun
Qin, Donghao
Hao, Jiawei
Wu, Zhe
Zheng, Yutuo
Tang, Fan
Lin, Jian
Funding for this research was provided by:
Science and Technology Department of Zhejiang Province (No. IGF22H160060)
Wenzhou Municipal Science and Technology Bureau (No. ZY2021007)
Health Science and Technology Plan of Zhejiang Province (Nos. 2021KY794 and 2023KY147)
Article History
Received: 1 April 2026
Accepted: 24 August 2026
First Online: 9 September 2026
Declarations
Ethics approval and consent to participate: This retrospective study involving the institutional cohort was approved by the Medical Ethics Committee of The Second Affiliated Hospital of Wenzhou Medical University and Yuying Children’s Hospital of Wenzhou Medical University. The requirement for written informed consent to participate was waived by the same ethics committee because archived tissue samples and de-identified clinical data were used in this study. All procedures involving human participants, human data, and human tissue samples were performed in accordance with relevant guidelines and regulations, including the Declaration of Helsinki, GCP, and ICH-GCP. In addition, the public TCGA and CGGA datasets used in this study are de-identified and publicly accessible; therefore, no additional ethical approval or informed consent was required for those data.
Consent for publication: Not applicable.
Competing interests: The authors declare that they have no competing interests.