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Authors
Ikeda, Shin-ichi
Sone, Kohei
Takai, Yoshihiro
Miyano, Takayuki
Negishi, Kazuno
Tsubota, Kazuo
Kurihara, Toshihide
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Funding
Funding for this research was provided by:
Grants-in-Aid for Scientific Research (KAKENHI) from the Ministry of Education, Culture, Sports, Science, and Technology (20K09834, 24K12770)
grant for myopia research from Tsubota Laboratory, Inc.
a grant for myopia research from Rohto Pharmaceutical Co., Ltd.
Japan Agency for Medical Research and Development (JP22gm1510007)
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Article History
Received: 16 January 2025
Accepted: 16 June 2025
First Online: 1 July 2025
Declarations
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: All animal experiments conducted in this study were approved by the Animal Experimental Committee of Keio University (permit number: 16017). The experiments adhered to the Institutional Guidelines on Animal Experimentation at Keio University, the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research, and the ARRIVE Guidelines for reporting animal research.
: Not applicable.
: We received grants from Tsubota Laboratory and Rohto Pharmaceutical Co., Ltd. during the study. K.T. served as the chief executive officer of Tsubota Laboratory. K.S., Y.T., and T.M. were employees of Rohto Pharmaceutical Co., Ltd. Additionally, S.I., K.T., and T.K. are co-applicants for the international patent WO2018/164113, which has already been registered in Japan. The sponsors had no control over the experiments, interpretation, writing, or publication of this work. S.I., T.K., and K.T. hold stock in Tsubota Laboratory. N.K. declares no competing interests.
