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Article History

Received: 22 March 2022

Accepted: 8 June 2022

First Online: 17 June 2022

Declarations

:

: The data used in this analysis is a subset of data from two published multicenter studies. Cases were from 7 hospitals, each received approval to participate, including a requirement for written informed consent, by the authorized ethics authority. It was collected at the following hospitals, the authorizing ethics authority for each site is noted. The centers, in order of number of subjects included, are as follows: Emma Children’s Hospital, The Netherlands [AMC University of Amsterdam]; University Medical Center of Ulm [University of Ulm]; Leiden University Medical Center, The Netherlands [AMC University of Amsterdam]; Silesian Institute Mother and Newborn, Poland {Medical University of Silesia]; James Cook University Hospital, United Kingdom [Health Research Authority, Newcastle & Tyneside]; Vittore Buzzi Children’s Hospital, Italy [University of Milan]; Alberta Children’s Hospital, Canada [University of Calgary] All experimental protocols were approved by the named institutional and/or licensing committee.

: Not applicable, the manuscript contains no person or copyrighted material.

: The institutions of TB, WO and AvK receive funding from the manufacture of the ventilator used in this study, but that funding did not include the work of the study. GL receives educational honoraria from the manufacture of the ventilator. The other authors declare no competing interests. The manufacture of the ventilator used in this study had no part in the study design and has not reviewed the results.