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Authors
Bracken, Abbey https://orcid.org/0000-0002-5110-1376
Lane, Steven
Siner, Sarah
Jones, Dawn
Lambert, Caroline
Mehta, Fulya
Eyton-Chong, Chin-Kien
Davis, Peter https://orcid.org/0000-0003-0669-2485
Fitzsimons, John https://orcid.org/0000-0001-9431-9749
Lim, Emma https://orcid.org/0000-0002-5403-3065
Clerihew, Linda
Carter, Bernie https://orcid.org/0000-0001-5226-9878
Sefton, Gerri
Carrol, Enitan D. https://orcid.org/0000-0001-8357-7726
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Funding
Funding for this research was provided by:
National Institute for Health and Care Research (II-LA-0216-20002)
National Institute for Health and Care Research (II-LA-0216-20002)
National Institute for Health and Care Research (II-LA-0216-20002)
National Institute for Health and Care Research (II-LA-0216-20002)
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Article History
Received: 29 April 2024
Accepted: 9 May 2025
First Online: 2 July 2025
Declarations
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: Ethics approval was given for the study by the regional ethics committee; North West– Liverpool Central Research Ethics Committee (REC 17/NW/0533) and Health Research Authority (HRA) permission to proceed was issued (IRAS ID 215339).
: Not applicable.
: GS and PD are members of NHS England SPOT (Systematic Paediatric Observation Tracking) Clinical Advisory Group. PD is chair of NHS England Paediatric Critical Care Clinical Reference Group. The remaining authors do not have competing interests.
: Vital signs documentation and sepsis screening form part of routine clinical care and consent was not required for the devices to record these changes. Posters outlining the purpose of the DETECT study were displayed in in-patient wards, giving permission to parents to decline the use of their child’s anonymised vital signs data in analysis. Informed consent was collected for families of children transferred to critical care, including statements about the use of anonymised data for publication as stated in the DETECT study protocol paper18.
: This study uses vital signs data collected for patients admitted to hospital, who had a subsequent critical deterioration. This is part of the NIHR funded DETECT study [Dynamic Electronic Tracking and Escalation to reduce Critical care Transfers]. This trial is funded by the National Institute of Health Research Invention for Innovation (NIHR i4i) Programme, funder reference II-LA-0216-20002. The study is supported by the NIHR Clinical Research Network North West Coast.Disclaimer: The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Neither the Sponsor nor the Funder had any role in the study design; collection, management, analysis, and interpretation of data; writing of this manuscript or in the decision to submit this manuscript for publication.Clinical trial number: not applicable.
