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Article History

Received: 22 March 2018

Accepted: 17 September 2018

First Online: 24 September 2018

Ethics approval and consent to participate

: The study was approved by the Ethics Committee of the Friedrich- Schiller-University at the Medical Faculty (Jena, Germany). Written informed consent was obtained from all patients before study intake.

: Not applicable.

: The authors declare that they have no competing interests. All authors had financial support from BMBF for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous 3 years; no other relationships or activities that could appear to have influenced the submitted work.

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