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Article History

Received: 15 June 2018

Accepted: 22 August 2019

First Online: 2 September 2019

Ethics approval and consent to participate

: This study was approved by the Institutional Review Board and Ethics Committee of Nagoya City University Graduate School of Medical Science (no. 708) and conducted in accordance with the principles laid down in the Declaration of Helsinki. After an in-depth explanation of the study’s purpose and methods, written consent was obtained from all eligible patients and caregivers.

: Not applicable.

: NS has received a lecture fee from Dainippon-Sumitomo. NW has received research funds from the Japanese Ministry of Health Labor and Welfare, the Japanese Ministry of Education, Science, and Technology, from the National Center of Neurology and Psychiatry, as well as an Intramural Research Grant for Neurological and Psychiatric Disorders. He has also received royalties from Sogensha and Akatsuki. KF has received research funds from the Japanese Ministry of Education, Science, and Technology. She has also received lecture fees from MSD. HS declares no conflicts of interest. TA has received lectures fees and/or research funds from Daiichi-Sankyo, Dainippon-Sumitomo, Eizai, Hisamitsu, Lilly, MSD, Meiji-seika Pharma, Mochida, Pfizer, Novartis, Shionogi, Takeda, Tanabe, Terumo, and Yoshitomi. He has received royalties from Igaku-Shoin, Kagakuhyoron-sha, and Seiwa shoten. The Japanese Ministry of Education, Science, and Technology and the Japanese Ministry of Health, Labor, and Welfare, Nagoya City University, the Japan Agency for Medical Research and Development, the Foundation for Promotion of Cancer Research, and the Yuumi Memorial Foundation for Home Health Care have funded his research projects.