Xu, Li
Yang, Haidong
Chen, Wanming
Yang, Man
Zhang, Jing
Zhang, Xiaobin
Tang, Xiaowei
Funding for this research was provided by:
Guidance Project of Jiangsu Provincial Health Commission (Z2023074)
Science Foundation of Kangda College of Nanjing Medical University (KD2023KYJJ130)
Suzhou Clinical Medical Center for Mood Disorders (Szlcyxzx202109)
Suzhou Key Laboratory (SZS2024016)
Suzhou Multicenter Clinical Research Project on Major Diseases (DZXYJ202413, MR-32-25-054378)
Yangzhou Basic Research Program (Joint Special Project) Health Project (2024-2-19)
Article History
Received: 7 September 2025
Accepted: 20 October 2025
First Online: 18 November 2025
Declarations
:
: The study protocol was approved by the Institutional Review Committee of Lianyungang Fourth People’s Hospital (Approval No. 2021LSYYXLL-P03, dated March 4, 2021) and conducted in accordance with the ethical principles for medical research involving human subjects described in the Declaration of Helsinki. Prior to inclusion in this study, informed consent was obtained from all participants and/or their legal guardians. All patients’ capacity to consent was assessed by two independent psychiatrists through clinical evaluation of their understanding of the study purpose, procedures, potential risks and benefits, and their ability to make voluntary decisions.
: Not applicable.
: The authors declare no competing interests.