Xu, Xiuli
Wang, Yinfen
Ye, Shaohui
Meng, Cuicui
Zhang, Qi
Deng, Lin
Wu, Guifu
Wang, Tong
Funding for this research was provided by:
Futian Healthcare Research Project (FTWS2025003)
Futian Healthcare Research Project (FTWS2025005)
National Natural Science Foundation of China (82570526)
Sanming Project of Medicine in Shenzhen (SZSM202402020)
Shenzhen Science and Technology Program (KCXFZ20230731094100002)
Article History
Received: 28 October 2025
Accepted: 17 June 2026
First Online: 24 June 2026
Declarations
:
: This study received ethical approval from the Institutional Review Board of the Eighth Affiliated Hospital of Sun Yat-sen University (approval code: 2025-021-02; approval date: 23 April 2025) and is formally registered with Chinese Clinical Trial Registry (Registration ID: ChiCTR2500101872). The investigator XX will provide eligible participants with a full verbal and written explanation of the study objectives, study procedures, and participants’ rights. Written informed consent forms will be obtained from all participants or their legal representatives before enrollment.
: This study will comply with the Declaration of Helsinki and local ethical regulations, and there are provisions for publication authorization in the participant consent forms.
: Participant recruitment commenced in June 2024 and is projected to conclude by June 2026. The Institutional Review Board of the Eighth Affiliated Hospital, Sun Yat-sen University, indirectly supervises trial progress through annual report-based periodic reviews.
: The authors declare no competing interests.