Li, Enguang
Ai, Fangzhu
Cai, Peipei
Wen, Kuo
Guo, Botang
Wen, Hongjuan https://orcid.org/0009-0007-0265-1690
Funding for this research was provided by:
National Natural Science Foundation of China (82607167)
Science and Technology Project of the Jilin Provincial Administration of Traditional Chinese Medicine (2024260)
Changchun University of Traditional Chinese Medicine Theme Case Project (2024YJ03)
2025 Thematic Case Project of the Development Center for Degree and Graduate Education, Ministry of Education (ZT-2510199001)
Article History
Received: 6 June 2026
Accepted: 28 September 2026
First Online: 11 October 2026
Declarations
Ethics approval and consent to participate: Ethics approval was granted by the Ethics Committee of the Affiliated Hospital of Changchun University of Chinese Medicine (CCZYFYLL-SQ-2024-227) and the Shenzhen Luohu People’s Hospital Research Ethics Committee for the external-center study (2024-LHQRMYY-KYLL-071). The Shenzhen committee approved the study protocol and written informed-consent form. All procedures complied with the Declaration of Helsinki and its later amendments, and written informed consent was obtained from all participants.
Consent for publication: Not applicable.
Study registration and protocol availability: This observational cross-sectional study was not prospectively registered. Analysis and implementation code supporting the reported workflow and the versioned reproducibility materials have been deposited in the public GitHub repository and versioned Zenodo record described above; this retrospective archiving should not be interpreted as prospective registration or as evidence of a prospectively registered protocol.
Competing interests: The authors declare no competing interests.