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Article History

Received: 17 August 2021

Accepted: 30 December 2021

First Online: 15 January 2022

Declarations

:

: The Ethical Committee of the Medical Faculty at the University of Würzburg, Germany, approved the study protocol (No.35/18). All analyses were performed as remote data queries on already fully anonymized data from the Research Data Centers (RDC) of the Federal Statistical Office and Statistical Offices of the Länder (Germany), DRG-Statistik 2010-2019, based on own calculations (project 3730-2018). All analyses were performed in accordance with the data protection requirements of the Federal Statistical Office. This included that only aggregated data were reported by the Federal Statistical Office, but not datasets of individual patients. Furthermore, subgroups with less than 3 persons in result files were censored by the Federal Statistical Office to guarantee patient anonymity for patients with rare health conditions.

: Not applicable.

: AS received research grants, speaker’s fees, and/or fees for participation in advisory board meetings and travelling grants from GlaxoSmithKline, Pfizer Pharma, Janssen-Cilag and MSD. JGL received research grants, speaker’s fees, and fees for participation in advisory board meetings from GlaxoSmithKline, Pfizer Pharma, Janssen-Cilag, SPMSD, and MSD. DG and PN declare that they have no competing interests.