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Article History

Received: 6 August 2024

Accepted: 13 December 2024

First Online: 31 December 2024

Declarations

:

: This study was conducted in full compliance with the ethical principles outlined in the Declaration of Helsinki, which provides guidance on ethical standards for medical research involving human participants. Ethics approval was granted by the Mexican Ministry of Health, the Mexican National Council of Science and Technology (0595 P-M), the Central Oxford Research Ethics Committee (C99.260) and the Ethics and Research Commissions from the Medicine Faculty at the National Autonomous University of Mexico (FMED/CI/SPLR/067/2015). All ethics committees that reviewed and approved the study provided their opinions in alignment with the Declaration of Helsinki. Participants gave informed consent to participate in the study before taking part.

: For the purposes of open access, the authors have applied a Creative Commons Attribution (CC BY) license to any Author Accepted Manuscript version arising.

: JRE reports grants to the University of Oxford from AstraZeneca and Regeneron Pharmaceuticals. All other authors declare no competing interests.

: An unauthorised version of the Spanish MMSE was used by the MCPS study team without permission. The MMSE is a copyrighted instrument and may not be used or reproduced in whole or in part, in any form or language, or by any means without written permission of PAR.