Document is current

Article History

Received: 6 August 2024

Accepted: 31 January 2025

First Online: 22 March 2025

Declarations

:

: CPRD research data services are provided by the Medicines and Healthcare products Regulatory Agency (MHRA), with support from the National Institute for Health and Care Research (NIHR), under the Department of Health and Social Care. CPRD collects anonymised patient data from a network of GPs across the UK. This primary care data is linked with various other health-related data to create a comprehensive, longitudinal dataset representing the UK population’s health. CPRD has ethical approval from the Health Research Authority (HRA) to facilitate research using anonymised patient data, reference: East Midlands—Derby Research Ethics Committee (REC): 21/EM/0265. For more details, visit: , , and .To access CPRD data, researchers must complete a study protocol, which is reviewed through CPRD’s Research Data Governance (RDG) process (previously known as ISAC). Independent scientific and patient input is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). The RDG process ensures that research using CPRD data is methodologically sound, serves the public interest, and maintains public and professional trust. Informed consent from individual patients is not required because the data managed by CPRD is anonymised.This study protocol received scientific and ethical approval through this process; the MHRA Independent Scientific Advisory Committee (ISAC: Protocol No. 20_000220).

: Not applicable.

: The authors declare no competing interests.