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Authors
Zhao, Wenya
Feng, Siyuan
Zhao, Mingli https://orcid.org/0009-0009-5745-8905
Zhuo, Yijia
Zhao, Xinyue
Wang, Xue
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Funding
Funding for this research was provided by:
Minhang Municipal Health Commission foundation of Shanghai (2023MW01, 2023MW01, 2023MW01, 2023MW01, 2023MW01, 2023MW01)
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Article History
Received: 22 April 2025
Accepted: 29 July 2025
First Online: 31 August 2025
Declarations
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: All participants provided written informed consent prior to enrollment. Ethical approval was obtained from the Ethics Committee of Life Sciences at Zhengzhou University (Reference No. ZZUIRB2023-265; approved in July 2023). The study was registered with the Chinese Clinical Trial Registry (Registration No. CTR2300077455; see Supplementary Files). All procedures were conducted in accordance with the Declaration of Helsinki. Informed consent was obtained from all participants after clearly explaining the study’s purpose and objectives. Confidentiality was strictly maintained, and participants were assured of their right to privacy and freedom to withdraw voluntarily at any stage, confirming their uncoerced agreement to participate.
: Written informed consent for publication was obtained from all study participants.
: The authors declare that there are no conflicts of interest related to this study.
