He, Guanhao
Huang, Zhongguo
Shi, Yan
Huang, Zishan
Wang, Di
Guo, Mengen
Guo, Yanfei
Xu, Jiahong
Hu, JianXiong
Dong, Xiaomei
Xiao, Jianpeng
Lin, Ziqiang
Liu, Tao
Wu, Fan
Ma, Wenjun
Funding for this research was provided by:
Medical and Young Elite Scientists Sponsorship Program by CAST (2022QNRC001)
National Natural Science Foundation of China (42505175)
National Natural Science Foundation of China (42075173)
National Key Research and Development Program of China (2023YFC3605000)
Article History
Received: 16 March 2024
Accepted: 17 October 2025
First Online: 8 December 2025
Declarations
:
: The SAGE study was approved by the Ethics Review Committee of the World Health Organization and the Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, China. Specifically, the baseline investigation was approved by the Ethics Committee of the Chinese Center for Disease Control and Prevention (approval number 200601), and the second and third waves were approved by the Shanghai Municipal Centre for Disease Control and Prevention (approval numbers 2014-8 and 2018-1, respectively). The study was conducted in accordance with the Declaration of Helsinki. Informed consent has been obtained from all study participants.
: Not applicable.
: The authors declare no competing interests.