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Article History

Received: 28 November 2025

Accepted: 9 February 2026

First Online: 23 February 2026

Change Date: 19 May 2026

Change Type: Update

Change Details: Following the article's publication, an error was found in Supplementary Material 3. This has been corrected.

Declarations

:

: The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the International Agency for Research on Cancer (IARC/WHO) Ethics Committee (IEC 24–39 and IEC 25–25) and by the Instituto Nacional de Saúde Doctor Ricardo Jorge (INSA) (163/2024).All subjects gave their written informed consent prior to enrolment in the study.

: Not applicable, as all data were de-identified prior to analysis and no individual details are presented.

: The authors declare no competing interests.