Nagata, Jun
Sekine, Ayumi
Tanabe, Nobuhiro
Taniguchi, Yu
Ishida, Keiichi
Shiko, Yuki
Sakao, Seiichiro
Tatsumi, Koichiro
Suzuki, Takuji
Funding for this research was provided by:
Uehara Memorial Foundation (Research Fellowship for Young Investigators 2019)
Grant-in-Aid for Scientific Research(Japan Society for the Promotion of Scienc (19K17626)
Japanese Ministry of Health, Labour and Welfare research grants (No.16ek0109127h0002, No.16ek0109127h0002, No.16ek0109127h0002)
Article History
Received: 16 March 2022
Accepted: 12 July 2022
First Online: 20 July 2022
Declarations
:
: This study was conducted in accordance with the tenets of the amended Declaration of Helsinki. Patient identity was concealed in this study, and data were compiled according to the requirements of the Japanese Ministry of Health, Labour and Welfare, which is dedicated to privacy, information technology, and civil rights. The research protocol for this study was approved by the Research Ethics Committee of the Chiba University School of Medicine (Approval No.: 2584); we had already performed "opt-out" by notifying or disclosing information. Written informed consent was obtained from all patients who were enrolled since 2009, when this requirement became mandatory (Approval No.: 826). In the case of patients who died before 2008, written informed consent was obtained from their next of kin when we examined prognosis in the relevant study (Approval No.: 84). The study database was anonymized, and all experiments were performed in accordance with the relevant guidelines and regulations.
: Not applicable.
: AS has received honoraria for lectures from Jansen Pharmaceutical K.K., Nippon Shinyaku Co, Ltd., and Mochida Seiyaku Co, Ltd., as well as research grant support from Jansen Pharmaceutical K.K. and Nippon Shinyaku Co, Ltd. NT has received honoraria for lectures from Jansen Pharmaceutical K.K., Nippon Shinyaku Co, Ltd., and Bayer Yakuhin, Ltd., as well as research grant support from Pharmaceutical K.K. and Nippon Shinyaku Co, Ltd. YT has received honoraria for lectures from Jansen Pharmaceutical K.K., Daiichi Sankyo Co, Ltd., and Bayer Yakuhin, Ltd., as well as research grant support from Jansen Pharmaceutical K.K. and Nippon Shinyaku Co, Ltd. SS has received honoraria for lectures from Jansen Pharmaceutical K.K., Nippon Shinyaku Co, Ltd., and Bayer Yakuhin, Ltd. KT has received honoraria for lectures from Jansen Pharmaceutical K.K. and Nippon Shinyaku Co, Ltd. The funders had no role in the study design, data collection or analysis, decision to publish, or preparation of the manuscript. The other authors declare no conflicts of interest.