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Article History

Received: 29 May 2022

Accepted: 9 August 2022

First Online: 14 August 2022

Declarations

:

: The study protocol was approved by the Research Ethics Committee of the Northern Savo Hospital District (statement 80/2014) and Tampere University Hospital (R15149), and the study was conducted in compliance with the Declaration of Helsinki (as revised in 2013). A written informed consent was obtained from all participants.

: Not applicable.

: MM: personal consulting fee, congress travel costs and a lecture fee from Boehringer Ingelheim, congress travel cost from Roche, outside the submitted work. ES: personal consulting fee and congress travel cost from Boehringer Ingelheim, congress travel cost from Novartis Finland and Orion Pharma, owns personal stocks from Orion LTD, outside the submitted work. SS: owns personal stocks from Merck & Co, Faron Pharmaceuticals, CRISPR Theraupeutics, and 3 M Co. outside the submitted work. HN: personal lecture fees from Boehringer Ingelheim and Roche, congress travel cost from Boehringer Ingelheim, Sanofi-Genzyme, and Chiesi, outside the submitted work. MK: participation on GlaxoSmithKline advisory board, outside the submitted work. HK: owns personal stocks from Orion LTD, outside the submitted work. RK: personal consulting and lecture fees, advisory board member Boehringer Ingelheim, lecture fee from Roche, congress travel cost from Orion Pharma, virtual congress travel cost from Roche and Novartis, advisory board member MSD, outside the submitted work. MP: personal lecture fee, congress travel cost and advisory board member Boehringer Ingelheim, lecture fee Roche, congress travel cost Orion Pharma, outside the submitted work. HH, H-PK, TS, JR, JL, and TU declare that they have no competing interests.