Salmaso, Anita
Samarelli, Anna Valeria
Moscatiello, Giulia Yuri
Raineri, Giulia
Cagnotto, Alfredo
Bigini, Paolo
Clini, Enrico
Tonelli, Roberto
Morelli, Annalisa
Article History
Received: 24 January 2025
Accepted: 17 October 2025
First Online: 24 November 2025
Declarations
:
: The Mario Negri Institute for Pharmacological Research IRCCS adheres to the principles outlined in the following laws, regulations, and directives concerning the care and use of laboratory animals: Italian law (D.lgs 26/2014; Authorization No. 19/2008-A issued on March 6, 2008 by the Ministry of Health); the Mario Negri Institutional Regulations and Policies—which provide internal authorization for persons conducting animal experiments (Quality Management System Certificate, UNI EN ISO 9001:2015, Reg. No. 6121); the NIH Guide for the Care and Use of Laboratory Animals (2011 edition); and the EU Directives and Guidelines (EEC Council Directive 2010/63/UE). This work was reviewed by the IRCCS-IRFMN Animal Care and Use Committee (IACUC) and subsequently approved by the Italian “Istituto Superiore di Sanità” (Code: 558/2021-PR).
: Not applicable.
: The authors declare no competing interests.