He, Wenqiang
Li, Xueping
Huang, Haining
Tang, Zitong
Zhu, Junqing
Yang, Yuqiong
Chen, Zizheng
Miao, Chengyu
Yang, Huajing
Zha, Shanshan
Zhou, Zifei
Liu, Jiachun
Liang, Zhenyu
Chen, Rongchang
Wang, Fengyan
Funding for this research was provided by:
the National Natural Science Foundation of China (82270044)
the National Natural Science Foundation of China (82200044)
the National Key Research and Development Program of China (2017YFC1310600)
the grant of State Key Laboratory of Respiratory Disease (SKLRD-Z-202317)
Article History
Received: 12 December 2025
Accepted: 6 February 2026
First Online: 27 February 2026
Declarations
:
: This study was approved by the Institutional Review Board of the First Affiliated Hospital of Guangzhou Medical University (Approval No.2017-22),registered with the International Clinical Trials Registry (ClinicalTrials.gov, NCT03240315, registration date: July 31, 2017, first posted on August 7, 2017), and was conducted in accordance with the Declaration of Helsinki (2008). Written informed consent was obtained from all participants prior to enrollment.
: Not applicable.
: The authors declare no competing interests.